Loading clinical trials...

IV Acetaminophen and Patent Ductus Arteriosus | Clinical Trials | Clareo Health

COMPLETEDNA

IV Acetaminophen and Patent Ductus Arteriosus

The Efficacy of IV Acetaminophen on Patent Ductus Arteriosus Closure in Preterm Infants

NCT03008876•Albany Medical College

Summary

This is a randomized controlled trial to evaluate the efficacy of IV acetaminophen versus IV ibuprofen in closing a hemodynamically significant patent ductus arteriosus in preterm infants.

Eligibility

Age

0 - 0 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•preterm infants 23-30 weeks gestation,
•PDA requiring treatment

Exclusion Criteria

•infection,
•congenital heart disease,
•genetic syndrome,
•NEC,
•pulmonary hypertension,
•hydrops,
•intestinal perforation,
•grade 3 or 4 IVH,
•serum creatinine \>1.5,
•previous treatment with a COX inhibitor.

Locations (1)

Albany Medical Center Neonatal Intesive Care Unit

Albany, New York, United States

Key Dates

Start Date

January 1, 2017

Primary Completion Date

June 30, 2019

Completion Date

June 30, 2019

Last Updated

July 8, 2019

Enrollment

ACTUAL participants

Conditions

Patent Ductus Arteriosus

Interventions

Acetaminophen

DRUG

Ibuprofen

DRUG

PDA for Kidneys Study

NCT06658496

Patent Ductus ArteriosusCongenital Heart Disease

View study

RECRUITINGEARLY_PHASE1

The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease

NCT06298344

Congenital Heart DiseaseThiamine Deficiency+3 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 8, 2019Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

IV Acetaminophen and Patent Ductus Arteriosus

Inclusion Criteria

Exclusion Criteria

PDA for Kidneys Study

The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease

The Effectiveness of Paracetamol Versus Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Neonates

Research on the Individualized Treatment Strategy for Extremely Preterm Infants With hsPDA Based on Biomarkers and Targeted Delivery Systems

Noninvasive Hemodynamics Assessment of Preterms With Successful Medical Closure of PDA

Canadian National PDA Treatment Study