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Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.
Preclinical data obtained using an Caco-2 intestinal cell model and enzyme assays suggest phenolic-rich potato extracts decrease intestinal glucose transport. The aim is to determine if these effects extend to the the an in vivo situation. Specifically, the glycemic response following consumption of phenolic rich pigmented potatoes compared to white potatoes with lower phenolic content will be measured. Gastric emptying will also be measured to show the effects are in fact due to rate of carbohydrate digestion and intestinal glucose transport and not gastric emptying rate.
Age
18 - 50 years
Sex
ALL
Healthy Volunteers
Yes
Start Date
January 1, 2016
Primary Completion Date
February 1, 2016
Completion Date
June 1, 2016
Last Updated
October 6, 2016
11
ACTUAL participants
Purple Majesty potato chips
OTHER
Mountain Rose potato chips
OTHER
White potato chips
OTHER
Crackers
OTHER
Lead Sponsor
Purdue University
Collaborators
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT06005415