Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine Treatment

Exclusion Criteria

• •1. Pregnancy/lactation
• •2. Medical condition requiring immediate investigation or treatment
• •3. Recent (\< 6 months)/current history of drug abuse/dependence (other than caffeine, or nicotine)
• •4. Lifetime history of psychosis, other Axis I comorbidities are allowable
• •5. Significant Axis II diagnosis
• •6. Previous intolerance or failure to respond to an adequate trial of desvenlafaxine
• •7. Failure of \> 2 antidepressant treatments of adequate dose and duration for current MDE
• •1. Pregnancy/lactation
• •2. Medical condition requiring immediate investigation or treatment
• •3. Lifetime history of any psychiatric disorder
• •4. Lifetime history of receiving an antidepressant