Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hospices Civils de Lyon
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Diagnosis of schizophrenia according to DSM 5.0 (Diagnostic and Statistical Manuel 5.0) criteria
2. Presence of symptoms despite the optimization of the antipsychotic dosage (based on prescriber's judgment) for at least 6 weeks, i.e. a dosage increase cannot be considered due to tolerability issues and/or is judged unlikely to bring sufficient clinical improvement. This will be operationalized by a minimum Negative PANSS score of 20 and at least one item scoring \> 4; OR a minimum Positive PANSS score of 20 with at least one item scoring \> 4 (e.g. delusion or hallucination), indicating persistent negative symptoms and/or persistent positive symptoms,
3. Patient under curatorship/guardianship or not
4. Age between 18 and 65 years old.
5. Covered by, or having the right to Social Security
6. Patient who understands the French language
7. Informed consent signed
You may not be if
1. Other neuropsychiatric disorders (psychiatric history will be assessed using the MINI 6.0 (Mini International Neuropsychiatric Interview 6.0)) including bipolar disorders and mood depression disorders - (NB: Patients with substance related and addictive disorders will not be excluded from the study, but these data will be carefully recorded).
2. Contraindications for tDCS (neurologic stimulator, pacemaker, cardiac defibrillator, cardiac prosthesis, vascular prosthesis, intracranial clips or clamps, cerebrospinal fluid derivation, metallic splinters in the eyes),
3. Increase in total composite PANSS score of at least 20% between screening and enrollment visits
4. Women who are pregnant
5. Patients whose clinical condition requires in patient procedure under constraint
Clareo Health | STIM'ZO : Examining tDCS as an add-on Treatment for Persistent Symptoms in Schizophrenia
