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The aim of this study is to investigate the effects of non invasive brain stimulation - NIBS - techniques (Electroconvulsivotherapy - ECT, transcranial Direct Current Stimulation - tDCS, repetitive transcranial magnetic stimulation - rTMS) on serum Brain Derived Neurotrophic factor (BDNF) levels in patients with depression and schizophrenia. Four blood samples will be collected in each participants, one before the NIBS sessions, and 3 after the completion of NIBS protocols: one immediately after the end of the NIBS sessions, a second one week after and a last one month after. Two blood samples separated by one month will also be collected in a a group of healthy volunteers.
The hypothesis is that NIBS will modulate BDNF levels and that the modification in serum BDNF levels will be correlated with clinical improvements in the sample of patients.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Hopital Le vinatier
Bron, France
Start Date
December 1, 2010
Primary Completion Date
December 31, 2018
Completion Date
June 30, 2019
Last Updated
August 1, 2018
200
ESTIMATED participants
non invasive brain stimulation
DEVICE
Lead Sponsor
Hôpital le Vinatier
NCT07360600
NCT06793397
Data Source & Attribution
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