Loading clinical trials...

Analgesic Effects of Midazolam in Human Volunteers | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Analgesic Effects of Midazolam in Human Volunteers

A Single Center, Prospective, Randomized, Double Blind, Placebo-controlled, Three-way Cross-over Study of the Analgesic Effects of Midazolam Versus Placebo With Fentanyl as an Active Control in Human Volunteers

NCT02629146•Wilhelminenspital Vienna

View on ClinicalTrials.gov

Summary

This study evaluates analgesic properties of midazolam compared to placebo and fentanyl. Each participant will receive all three drugs (midazolam, fentanyl, placebo) on three different occasions (study visits) and the effect on different pain stimuli will be tested.

Eligibility

Age

18 - 40 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•male and female volunteers
•18-40 years old
•healthy
•body mass index between 5th and 85th percentile
•Caucasian
•non smoker or moderate smoker (\<10 cigarettes per day)
•able to understand, write, and read German

Exclusion Criteria

•acute or chronic pain condition (except for mild day-to-day pain on \<5 days/month)
•previous (up to 5 days preceding the study) or current medications prescription or over-the-counter, especially analgesics
•symptoms of a clinically relevant illness in the 2 weeks before the first study day
•hypertension
•any known psychiatric condition
•abuse of alcoholic beverages, drug abuse
•known positive human immunodeficiency virus status
•any known medical condition which may interact with study medication, study objectives, or compliance of subject with study tasks
•participation in a clinical trial in the 4 weeks preceding the study
•known allergy against Midazolam
+5 more criteria

Locations (1)

Schmerzdiagnostik / Clinical Research Unit

Vienna, Vienna, Austria

Key Dates

Start Date

December 1, 2015

Primary Completion Date

March 1, 2016

Completion Date

March 1, 2016

Last Updated

March 11, 2016

Enrollment

ACTUAL participants

Conditions

Analgesic DrugsAntinociceptive Agents

Interventions

Midazolam

DRUG

Fentanyl

DRUG

Isotonic saline

DRUG

Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia

NCT07070050

Analgesic DrugsAnalgesic, Nonopioid+4 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 11, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions