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Effects of the Mechanical Peripheral Stimulation for Parkinson's Disease Rehabilitation | Clinical Trials | Clareo Health

COMPLETEDNA

Effects of the Mechanical Peripheral Stimulation for Parkinson's Disease Rehabilitation

Effects of the Mechanical Peripheral Stimulation for Parkinson's Disease Rehabilitation - A Randomized Clinical Trial

NCT02594540•Federal University of Health Science of Porto Alegre

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate safety and effectiveness of the peripheral mechanical stimulation of the feet on gait variables, clinical status, risk of falls, BDNF levels, immunological profile and brain functional connectivity changes in patients with Parkinson's disease.

Detailed Description

Patients will be submitted to 8 sessions of peripheral mechanical stimulation of the feet or sham stimulation along 4 weeks. Evaluations will be performed before and after the first session, after the forth and the eighth session.

Eligibility

Age

50 - 85 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Diagnosis of idiopathic Parkinson's disease based on clinical criteria, dopamine transporter (DaT) scans and/or magnetic resonance imaging;
•Able to walk 25 feet unassisted or with minimal assistance;
•Presenting freezing of gait;
•Aged between 50-85 years;
•Minimum score of 20 in the Mini Mental State Examination (MMSE);

Exclusion Criteria

•Secondary musculoskeletal disorder involving the lower limb, as chondral injuries, ligament and ankle sprains which may impede the realization of the gait by pain or motion disability;
•Peripheral neuropathy;
•Not attending all the treatment;
•Absolute contraindications for fMRI (just for fMRI examination);
•Presence of deep brain stimulation;

Locations (1)

Universidade Federal de Ciências da Saúde de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Key Dates

Start Date

December 1, 2015

Primary Completion Date

September 1, 2016

Completion Date

September 1, 2016

Last Updated

January 12, 2017

Enrollment

ACTUAL participants

Conditions

Parkinson's Disease

Interventions

Mechanical Peripheral Stimulation (GONDOLA)

DEVICE

Research Into the Safety of a New Agent (VT-5006) in People With and Without Parkinson's Disease

NCT07310264

Healthy Volunteers (HV)Parkinson's Disease (PD)

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RECRUITINGNA

Deep Brain Stimulation Therapy in Movement Disorders

NCT02119611

Parkinson's Disease

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RECRUITINGNA

Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) China Study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 12, 2017Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Effects of the Mechanical Peripheral Stimulation for Parkinson's Disease Rehabilitation

Inclusion Criteria

Exclusion Criteria

Research Into the Safety of a New Agent (VT-5006) in People With and Without Parkinson's Disease

Deep Brain Stimulation Therapy in Movement Disorders

Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) China Study

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

SAD Study in Patients With Parkinson's Disease and Motor Fluctuations