CIK in Treating Patients With Bladder Cancer

Exclusion Criteria

• •Patients who had upper urinary tract disease (e.g., vesico-ureteral reflux or massive stones) that would make multiple transurethral procedures risk;
• •Patients who had urethral strictures that would prevent endoscopic procedures and repeated catheterization;
• •Patients who had prior or concurrent upper urinary tract tumors;
• •Patients who had distant metastases by imaging studies;
• •Patients with uncontrolled infection; underlying disease that was severe or life-threatening;
• •Patients who were lactating;
• •ECOG perform status ≥ 2;
• •Patients who are suffering from auto immune diseases or patients who need to accept glucocorticoid treatment;
• •Patients who are pregnant or nursing;
• •Patients with active tuberculosis (highly positive skin tests allowed if no active disease);
• •Patients with disease that would preclude general anesthesia;
• •Patients with active intractable or uncontrollable infection.