Effect of Sufentanil and Ropivacaine

Effect of 0.5µg/ml Sufentanil and Ropivacaine Towards Pregnant Women and Fetus in Analgesia Labor

NCT02488291•Fudan University

Summary

The investigators study the efficacy of epidural sufentanil/ropivacaine for analgesia labor in primiparas so as to decrease perinatal complications of analgesia labor.

Detailed Description

A prospective study of 120 full-term parturients receiving labor analgesia were randomly assigned into 2 groups: the 0.5Sufen group (N=60), the 0.25Sufen group (N=60).

Eligibility

Age

25 - 35 years

Sex

FEMALE

Healthy Volunteers

Inclusion Criteria

•1. Patients had regular prenatal examinations at the outpatient clinic;
•2. They were between 25 to 35 years of age)
•3. They had a gestational age ≥37 weeks and \< 42 weeks;
•4. They had an estimated fetal weight ≥ 2,500 g and \< 4,200 g.

Exclusion Criteria

•a history of spinal surgery,
•platelet count \<100×109 /L ,
•coagulation disorder,
•sensorimotor disorder of lower extremity,
•leg pain,
•puncture point infection,
•heart disease history,
•pulmonary disease,
•liver and renal function disorder and
•a history of neuropsychiatry drugs.

Key Dates

Start Date

April 1, 2014

Primary Completion Date

June 1, 2015

Completion Date

June 1, 2015

Last Updated

August 12, 2020

Enrollment

120

ACTUAL participants

Conditions

Anesthesia Complications

Interventions

0.25 sufentanil

DRUG

0.5µg/ml sufentanil

DRUG

0.1% ropivacaine

DRUG