Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Norwegian University of Science and Technology
With
St. Olavs Hospital
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Informed and written consent
Chronic migraine with or without aura defined in International Classification of Headache Disorders (ICHD)-3 criteria
Failed at least 3 oral migraine prophylactic treatments
Duration of migraine at least 1 year before inclusion
Start of migraine before participant turned 50 years
Participant can make a distinction between migraine and other types of headache
You may not be if
If the criteria for medication-overuse headache (MOH) is fulfilled
Heart or lung disease
Any kind of systematic or local disease or illness that may significantly increase the risk of complications for the procedure related to injection
Psychiatric illness that hinders participation in the study
Known pregnancy or breast feeding
Inadequate use of contraceptives
Overuse or abuse of opioids
Abuse of medications, narcotics or alcohol
Anomalies which hinder or impede the used method of injection
Allergy or any other hypersensitivity reactions against marcain, lidocaine, xylocain or adrenalin, botulinum toxin type A, Botox or any of it's constituents or any other related medication
Treatment with medication that can interact with botulinum toxin type A
