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Verticality Perception - Dissociating Head and Trunk Contributors in Healthy Human Subjects
The purpose of this study is to evaluate the relative contribution of head- and trunk-based sensory systems to internal estimates of direction of gravity in healthy human subjects. To implement this assessment experimentally, the investigators will use a motor-driven 3D-turntable and a thermoplastic mask to keep the head in a stable, either roll-tilted (±30°) or aligned with the trunk. The investigators will then obtain measurements of the subjective visual vertical in seven different whole-body roll positions (max. 90° roll-tilt). Analysis will be driven by a state-of-the art Bayesian integration model. The investigators hypothesize that different sensory input signals are combined in a statistically optimal fashion.
Age
18 - 60 years
Sex
ALL
Healthy Volunteers
Yes
University Hospital Zurich, Dept. of Neurology
Zurich, Canton of Zurich, Switzerland
Start Date
October 1, 2014
Primary Completion Date
November 1, 2015
Completion Date
November 1, 2015
Last Updated
November 1, 2024
12
ACTUAL participants
Vestibular stimulation by use of the turntable (static roll-tilt while the head is roll-tilted relative to the trunk)
OTHER
3D-video-head impulse testing
OTHER
Vestibular-evoked myogenic potentials (VEMPs)
OTHER
Lead Sponsor
University of Zurich
Data Source & Attribution
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