Patients must be within the first three years of illness, i.e. first diagnosis of schizophrenia is no older than three years.
Age 18 to 65 years, male or female
Minimal initial PANSS score of 75 at baseline
Female patients of childbearing potential need to utilize a proper method of contraception.
Body Mass Index between 18 and 40
You may not be if
Lack of accountability (assessed by an independent psychiatrist)
History of treatment-resistant schizophrenia, defined as no response to at least two antipsychotics given for a minimum of 6 weeks each in an adequate dosage
Positive urine drug-screening for illicit drugs at screening (except cannabinoids and benzodiazepines)
Serious suicidal risk at screening visit (Subject to investigator's and independent psychiatrist's judgement: Poses a serious suicidal or homicidal risk at screening visit or has made a serious suicide attempt within the last 12 months prior to screening visit, or has exhibited homicidal behaviour at anytime during her/his lifetime)
Known intolerance or allergy to olanzapine or cannabidiol
Other relevant interferences of axis 1 (e.g. serious depression) according to diagnostic evaluation (MINI) including residual forms of schizophrenia
Pregnancy, as determined through a β-HCG pregnancy test, or lactation