Preliminary Study of a Vaginal Lubrication Ring to Treat the Symptoms of Vaginal Dryness

Exclusion Criteria

• •Use of hormone therapy
• •Undergoing any vulvar or vaginal procedures (biopsies, radiation in the last 3 months)
• •Active vulvar or vaginal injections/lesions or complaints, as well as undiagnosed abnormal genital bleeding
• •History of chronic pelvic pain, interstitial cystitis, vulvar vestibulitis, pelvic inflammatory disease within the past 12 weeks
• •Known current clinically evident cervical or vaginal infection
• •Postpartum or post-abortion endometritis, unless symptoms resolved at least 12 weeks prior to study entry
• •Current persistent, abnormal vaginal bleeding
• •History of inability to place an IVR
• •History of any abnormality of the vagina resulting in distortion of the vaginal canal or incompatible with IVR placement
• •Body habitus, or history of lower genital tract abnormalities or prior surgeries, which may not allow the vagina to be appropriately accessed
• •Known or suspected allergy or hypersensitivity to polyurethane or glycerol
• •Known current alcohol or illicit drug abuse
• •Participants who have not recovered from adverse events due to chemotherapy or radiation treatment for cancer
• •Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
• •Any condition that, in the opinion of the investigator or study staff that would constitute contraindications to participation in the study or would compromise ability to comply with the study protocol