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Aim of this study is verify if postoperative CPAP after laparoscopic prostatectomy may reduce the impact of postoperative respiratory failure, defined as occurrence of hypoxemia (PaO2\<60 mmHg) and/or reduction of Forced Expiratory Volume in 1 second (FEV1) beyond 70% of basal value.
Laparoscopic radical prostatectomy (LRP) is a wide used, well tolerated procedure. However, the general anesthesia, the need for pneumoperitoneum and Trendelenburg position may have detrimental effects on both pulmonary volumes and mechanics, and they may increase the risk of postoperative respiratory failure (PORF). Continuous positive airway pressure (CPAP) improves oxygenation and reduces the rate of re-intubation in the presence of PORF. The aim of our study is to investigate postoperative respiratory function and the likely benefits of the use of CPAP, compared with Venturi mask in terms of prevention of post-operative hypoxaemia and worsening of lung spirometry. CPAP is delivered with "CASTAR" Helmet by StarMed.
Age
18 - 70 years
Sex
MALE
Healthy Volunteers
No
Ospedale Luigi Sacco
Milan, Lombardy, Italy
Start Date
August 1, 2013
Primary Completion Date
July 1, 2014
Completion Date
July 1, 2014
Last Updated
July 11, 2014
48
ACTUAL participants
Continuous Positive Airway Pressure(CPAP)
DEVICE
Venturi Mask FiO2 40%
DEVICE
Lead Sponsor
ASST Fatebenefratelli Sacco
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