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Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation

NCT01943812•Peter Humaidan

Summary

The aim of this study is to compare two FET protocols by modifying the substituted FET cycle in order to maintain a higher ongoing positive pregnancy rate and thus reduce the early pregnancy loss. Hypothesis: adding GnRH-agonist to the substituted cycle in FET treatment reduces the early pregnancy loss.

Eligibility

Age

18 - 45 years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Endometrial thickness ≥ 7 mm after stimulation
•18-45 years
•IVF/ICSI fertilisation
•BMI \> 18,5 \<30 kg/m2
•cycle length 25-34 days

Exclusion Criteria

•endometrial thickness \< 7 mm or no triple layer endometrium and/or functional follicles
•Uterine abnormality
•Chronic medical disease
•oocyte donation cycles

Locations (2)

IVF syd

Fredericia, Denmark

Fertility Clinic Regional Hospital Skive

Skive, Denmark

Key Dates

Start Date

December 1, 2013

Primary Completion Date

April 1, 2019

Completion Date

April 1, 2020

Last Updated

June 23, 2020

Enrollment

287

ACTUAL participants

Conditions

Pregnancy LossFrozen Embryo Transfer

Interventions

Estradiol and progeterone

DRUG

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

NCT06408181

Pre-EclampsiaPregnancy Loss

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RECRUITING

Relaxin Measurement in Different Endometrial Preparation Approaches for Frozen Embryo Transfer

NCT06526520

Frozen Embryo Transfer

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RECRUITINGNA

Tender Loving Care for Recurrent Pregnancy Loss

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 23, 2020Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation

Inclusion Criteria

Exclusion Criteria

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

Relaxin Measurement in Different Endometrial Preparation Approaches for Frozen Embryo Transfer

Tender Loving Care for Recurrent Pregnancy Loss

Noninvasive Implantation Potential vs Morphology-Based Selection in IVF Single Blastocyst Transfer

Individualized Grief Support With Swanson Model

Sperm DNA Fragmentation in Recurrent Pregnancy Loss