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A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITING

A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities

NCT01857427•Ulysses Magalang MD

View on ClinicalTrials.gov

Summary

The primary objective of this study is to build a well characterized cohort of patients that will be used to determine the genetic variants associated with obstructive sleep apnea (OSA)and its co-morbidities.

Detailed Description

The purpose of building the cohort is to allow the performance of genome-wide association studies with a large sample of patients that have been well-characterized using standardized procedures.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•We will recruit subjects who are:
•18 years of age and older.
•Willing and able to give informed consent
•AND any of the following:
•PSG (polysomnogram)requested by a physician based on clinical grounds
•AHI (Apnea-hypopnea index) ≥ 5 episodes per hour based on a prior PSG.

Exclusion Criteria

•Incapable of giving informed consent
•Under the age of 18

Locations (1)

Suite 2600, Martha Morehouse Medical Pavilion

Columbus, Ohio, United States

Key Dates

Start Date

August 1, 2012

Primary Completion Date

December 1, 2025

Completion Date

December 1, 2025

Last Updated

July 24, 2025

Enrollment

5,000

ESTIMATED participants

Conditions

Obstructive Sleep Apnea

OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia

NCT06430957

Obstructive Sleep Apnea Risk ManagementPostoperative Complications+2 more

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RECRUITINGNA

Digital-supported Orofacial Myofunctional Therapy in OSA

NCT07292922

Obstructive Sleep Apnea (OSA)

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 24, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities

Inclusion Criteria

Exclusion Criteria

OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia

Digital-supported Orofacial Myofunctional Therapy in OSA

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

Diaphragm Ultrasound İn Children With OSAS

BodySleep Algorithm for OSA Diagnosis in Children