Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sensimed AG
Age
40–89
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age between 40 and 89 years old
Diagnosis of treated POAG (including normal tension glaucoma (NTG))
All IOP measurements during the VF period (to be described further) equal or lower than 18 mmHg and/or on average equal or lower than 16 mmHg in the same period
Documented glaucomatous VF damage at baseline, characterized by glaucoma hemifield test result outside normal limits on at least 2 consecutive VF tests or the presence of at least 3 contiguous test points within the same hemifield on the pattern deviation plot at p\<0.01, with at least 1 point at p \< 0.005
At least 8 visual field tests carried out within at least 2 years, all with fixation losses and false positive/negative results equal or less than 33%
For fast progressing eyes, 1) pointwise progression defined as two or more adjacent VF test locations in the same hemifield that show a threshold sensitivity rate of change more negative than -1.0 dB/year with p\<0.01 or 2) a global rate of VF change based on mean deviation (MD) more negative than -1.0 dB/year
For slowly or minimally progressing eyes a VF MD rate of change more positive than -0.5 dB/year with no significant pointwise progression as described above
Not more than 6 diopters spherical equivalent on the study eye
Have given written informed consent, prior to any investigational procedures
You may not be if
Baseline VF MD more negative than -15 dB. The rationale here is that in severely damaged visual fields, one may not be able to detect and measure rates of progression due to a 'floor effect'
Corneal or conjunctival abnormality precluding contact lens adaptation
Severe dry eye syndrome or other ocular disease
Patients with angle closure glaucoma, traumatic glaucoma or uveitic glaucoma
Patients with previous intraocular surgery in the enrolled eye, including cataract surgery
Patients with allergy to corneal anesthetic
Patients with contraindications for silicone contact lens wear
Patients not able to understand the character and individual consequences of the investigation
Participation in unrelated clinical research within the last 4 weeks
