Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Toronto Sunnybrook Regional Cancer Centre
With
Canadian Breast Cancer Foundation
The risk of moist desquamation in large breasted women remains unacceptably high and reactions tends to be severe and produce significant permanent and delayed side effects. Evidence suggests that the use of a prone breast IMRT technique has the potential to decrease the risk of moist desquamation in large breasted women to the levels that are now seen when average/smaller breasted women are treated with supine IMRT. As prone breast XRT is currently only offered at 6 of 15 of the Ontario Cancer Centres polled for the purposes of providing motivation for this study, a multicentre RCT is feasible to confirm and quantify the improvement provided by the prone technique and provide Level 1 evidence for it to be adopted world-wide.
Age
Any age
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
confirmed histological diagnosis of breast carcinoma or ductal carcinoma in situ (DCIS);
treated with BCT;
no indication for treatment of regional LN;
Women with a bra size of 40 inches or greater, or a pre-surgery cup size of D or greater
You may not be if
Regional Lymph Node XRT indicated;
Bilateral breast cancer;
unhealed wound (skin not closed and/or infection);
previous XRT to the same breast;
unable to lie prone;
presence of active connective tissue disease;
pregnancy;
unacceptable heart exposure (as measured by \> 10% of the heart receiving 50% of the prescribed dose, i.e. V25Gy \> 10%);
adequate coverage of postoperative tumour bed not technically possible
Clareo Health | The Prone Breast Radiation Therapy Trial
