Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vanderbilt University
Age
30–60
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Ambulatory females age 30-60 years old
Women of all ethnic groups
BMI≥35 kg/m2
Approval for Roux-en-Y gastric bypass or sleeve gastrectomy.
You may not be if
Smoking \>7 cigarettes per day
Previous malabsorptive or restrictive intestinal surgery
Pregnant or breastfeeding
Recent history of neoplasia (\<5 years ago)
Malabsorptive syndromes
Inflammatory intestinal disease
Patients with established organ dysfunction
Diagnosis of type 1 or type 2 diabetes mellitus or current use of anti-diabetic medication (last 30 days; last 60days for thiazolidinediones)
Diagnosed hyperbetalipoproteinemia or hypobetalipoproteinemia
Patients on cholesterol lowering medicines
Vegan diet
Hepatic fat content \<10% by MRI
Inability to comply with study protocol such as unable to make study visits or be available daily for phone contact
Any condition which would interfere with MRI or PET studies, e.g. claustrophobia, cochlear implant, chronic back pain limiting ability to lay flat, metal fragments in eyes, cardiac pacemaker, neural stimulator, tattoos with iron pigment and metallic body inclusions or other metal implanted in the body which may interfere with MRI scanning.
