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The Significance of the Vasopressin System of the Hemodynamics, Water Balance and Prognosis in Chronic Heart Failure
The purpose of this study is to determine the effect of fluid restriction and the neurohormonal mechanisms in the development of hyponatremia in patients with congestive heart failure and hyponatremia. The hypothesis is that strict fluid restriction leads to a larger increase in plasma sodium than standard treatment in patients with decompensated heart failure associated with hyponatremia. A secondary hypothesis is that the neurohormonal change is greater in patients treated with strict fluid restriction versus standard treatment.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Department of Cardiology, Copenhagen University Hospital, Rigshospitalet
Copenhagen, Denmark
Bispebjerg Hospital
Copenhagen, Denmark
Start Date
November 1, 2012
Primary Completion Date
November 1, 2016
Completion Date
November 1, 2016
Last Updated
October 28, 2015
40
ESTIMATED participants
Fluid restriction
OTHER
Lead Sponsor
Finn Gustafsson
Collaborators
NCT07484009
NCT07191730
Data Source & Attribution
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