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Management of Recurrent Croup | Clinical Trials | Clareo Health

TERMINATEDPHASE3

Management of Recurrent Croup

Management of Recurrent Croup: Comparison Between Inhaled Fluticasone and Oral Prednisolone

NCT01748162•University of Michigan

Summary

Presently children who experience recurring croup symptoms receive a variety of treatments. This is because it is not clear which treatments may be best. Some children are given inhaled steroids (similar to what children with asthma use). Others are carefully watched and cautioned to avoid potential triggers (certain foods, environmental allergens, etc), and should episodes of croup recur they are treated with a short course of oral steroids. The purpose of this study is to compare two safe and clinically appropriate methods for treating recurrent croup, daily inhaled steroids versus observation with oral steroids on an as needed basis, to see if either is useful in preventing future episodes of croup.

Eligibility

Age

0 - 15 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Pediatric population: 6 months to 15 years of age
•2 or more episodes of croup in 12 month period
•* croup defined as acute onset inspiratory stridor, barking cough, with respiratory distress.

Exclusion Criteria

•Grade 3 or 4 subglottic stenosis
•Subglottic hemangioma
•Posterior laryngeal cleft
•Recurrent respiratory papillomatosis
•External compression (Innominate artery compression, mediastinal mass, (double aortic arch, etc)
•Symptoms or signs suggesting another cause of stridor, such as epiglottitis, bacterial tracheitis, or supraglottic foreign body
•Tracheomalacia/ bronchomalacia severe enough to cause respiratory distress
•Current steroid therapy for previously diagnosed condition, i.e. reactive airway disease.
•Other medical conditions necessitating chronic steroid utilization

Locations (1)

University of Michigan

Ann Arbor, Michigan, United States

Key Dates

Start Date

September 1, 2012

Primary Completion Date

June 1, 2014

Completion Date

June 1, 2014

Last Updated

November 13, 2017

Enrollment

ACTUAL participants

Conditions

Croup

Interventions

Fluticasone

DRUG

Prednisolone IF needed

DRUG

Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma

NCT06560255

AsthmaRespiratory Tract Infections+9 more

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COMPLETEDNA

Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup

NCT06959407

LaryngotracheobronchitisCroup

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 13, 2017Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Management of Recurrent Croup

Inclusion Criteria

Exclusion Criteria

Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma

Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup

Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup

A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup