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A Phase II Study of Neoadjuvant Chemotherapy With Docetaxel, Capecitabine, Cisplatin, and Bevacizumab in Patients With Unresectable Advanced Gastric Cancer
The purpose of this study is to determine whether docetaxel, capecitabine, cisplatin, and bevacizumab are effective in the treatment of unresectable advanced gastric cancer.
In our previous phase II study of neoadjuvant docetaxel, capecitabine and cisplatin chemotherapy, patients with unresectable gastric cancer because of invasion to adjacent organs or metastasis to para-aortic lymph nodes received benefit from neoadjuvant chemotherapy. Based on these results and reports that bevacizumab enhances response rate, we planned docetaxel, capecitabine, cisplatin, and bevacizumab as neoadjuvant chemotherapy for patients with local invasion or para-aortic node metastasis alone.
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
No
Asan Medical Center
Seoul, South Korea
Start Date
July 1, 2010
Primary Completion Date
December 1, 2017
Completion Date
July 1, 2018
Last Updated
January 7, 2020
31
ACTUAL participants
Docetaxel, Capecitabine, Cisplatin, Bevacizumab
DRUG
Lead Sponsor
Asan Medical Center
Collaborators
NCT07259226
NCT07102901
Data Source & Attribution
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