Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Shanghai Zhongshan Hospital
Age
40–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
people aging from 40 to 80 with self ability of judgment
out-patients diagnosed as stable COPD according to "diagnosing and treatment guideline of COPD (2007 edition)" by Respiratory Department of Chinese Medical Association
PFT value at screen phase meet the standard as follows: FEV1/FVC \< 70% and FEV1% among 30%-80% 15 mins after inhalation of 400ug Ventolin (i.e., moderate and severe COPD patients ).
people who can use Tiotropium Bromide powder inhalation device
people who join the study voluntarily and sign ICF (Informed Consent Form)
You may not be if
people who have other acute or chronic respiratory diseases which may cause impairment of pulmonary function such as asthma
AECOPD （acute exacerbation of COPD）
people who got respiratory failure 1 month before the study
people who received oral corticoid treatment 1 month before the study
people who undergo oxygen therapy at home because of respiratory failure
people who are allergic to β2 receptor agonist such as tulobuterol
patients with Skin diseases such as atopic dermatitis, who are not appropriate to use transdermal patch
patients of hyperthyroidism, hypertension, heart disease and severe arrhythmia, diabetes mellitus, who are not appropriate to useβ2 receptor agonist
patients who have undergone pulmonary lobectomy or have tumor
active tuberculosis patients
people who got acute respiratory tract infection in a month or during screening phase
allergic rhinitis patients
glaucoma patients
people who have diseases which may cause dysuria such as prostatic hypertrophy or bladder neck occlusion
gestation, lactation and child-bearing age women who don't agree to take contraceptive measures during the study
people with abnormal live or kidney function, people with nervous system diseases, malignant tumor, neutropenia or other progressive basic diseases.
People who are mental retardation, mentally ill, deaf-mute or uncooperative, who cannot correctly describe their disease or do corresponding respiratory questionnaire.
People who are allergic to atropine and its derivatives (including tiotropium bromide and ipratropium bromide), lactose or any inhalant components.
people who have taken part in other medical clinical trial
other conditions that investigators think not appropriate for the study
Clareo Health | Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease
