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Prophylactic Endoscopic Coagulation for the Prevention of Bleeding in Endoscopic Mucosal Resection (EMR) of Large Sessile Colonic Polyps: A Multi-centre, Randomised Control Trial
The hypothesis of this study is that prophylactic coagulation therapy with coagulation forceps to visible vessels within the mucosal defect for colonic Endoscopic Mucosal Resection (EMR) will reduce the rate of delayed bleeding when compared with current established standard EMR technique.
Delayed bleeding from the site of the resection remains one of the most common complications following EMR, occurring in up to 12% of patients. The purpose of the study is to prevent such bleeding with the use of a technique known as: "coagulation therapy." This therapy involves using a small dose of heat energy that results in clotting(coagulation) of a blood vessel. It is already used widely in the stomach and we intend using this on a lower setting to blood vessels that are exposed after the resection.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Westmead Hospital
Westmead, New South Wales, Australia
Start Date
May 1, 2011
Primary Completion Date
January 1, 2014
Completion Date
August 1, 2015
Last Updated
March 27, 2025
328
ACTUAL participants
Prophylactic use of coagulation therapy
PROCEDURE
Lead Sponsor
Professor Michael Bourke
Data Source & Attribution
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