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Randomized Trial Comparing Digestive and Urinary Dysfunction Secondary to 2 Surgical Techniques Used in the Management of Deep Endometriosis Infiltrating the Rectum: Colorectal Resection and Rectal Nodules Excision (ENDORE)
The purpose of this study is to determine whether performing colorectal resection in deep endometriosis infiltrating the rectum is responsible for a higher rate of postoperative digestive and urinary dysfunction when compared to rectal nodules excision (conservation of the rectum).
The study compare digestive and urinary functional outcomes following surgical management of rectal endometriosis by either colorectal resection or conservative surgery (shaving or full thickness excision of rectal nodules). Patients managed for rectal endometriosis are randomized in two arms, and followed up for 24 months. The assessment of digestive and urinary functions is performed at 6, 12, 18 and 24 months using standardized questionnaires. Postoperative complications and improvement of endometriosis related pain are also recorded.
Age
18 - 45 years
Sex
FEMALE
Healthy Volunteers
No
Service de Gynécologie et Obstétrique, CHU Jean de Flandre
Lille, France
Service de Gynécologique-Obstétricale et Reproduction Humaine, Hôpital Tenon, Université Pierre et Marie Curie Paris 6
Paris, France
Rouen University Hospital
Rouen, France
Start Date
March 1, 2011
Primary Completion Date
September 1, 2013
Completion Date
September 22, 2015
Last Updated
October 6, 2025
60
ACTUAL participants
Rectal/colorectal segmental resection
PROCEDURE
Rectal nodule excision
PROCEDURE
Lead Sponsor
University Hospital, Rouen
Data Source & Attribution
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