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Validating The Prognostic Role of ATR Mutation in Patients With Endometrioid Endometrial Cancer
This research study is studying prognostic biomarkers in tissue samples from patients with endometrial cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PRIMARY OBJECTIVES: I. To validate the clinicopathologic associations and prognostic significance of ATR mutation in endometrioid endometrial cancer cases with defective DNA mismatch repair. OUTLINE: This is a multicenter study. DNA extracted from previously collected tumor samples is analyzed to validate the clinicopathologic associations and prognostic significance of ATR mutation.
Age
All ages
Sex
FEMALE
Healthy Volunteers
No
Gynecologic Oncology Group
Philadelphia, Pennsylvania, United States
Start Date
September 1, 2010
Primary Completion Date
May 1, 2014
Last Updated
August 23, 2017
2,824
ESTIMATED participants
Laboratory Biomarker Analysis
OTHER
Lead Sponsor
Gynecologic Oncology Group
Collaborators
NCT05334069
NCT07077876
Data Source & Attribution
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