Low Dose Radiation to Improve T-Cell Infiltration in Pancreatic Cancer

Inclusion Criteria

• •Radiological diagnosis of resectable pancreatic carcinoma is required prior to treatment. Potentially resectable is defined as no extrapancreatic disease, no evidence (on CT) of involvement of the celiac axis or superior mesenteric artery, no evidence (on CT or MRI) of occlusion of the superior mesenteric vein or superior mesenteric-portal venous confluence.
• •No evidence of metastatic disease as determined by chest CT scan, abdominal CT scan (or MRI)
• •18 years of age or older
• •American Society of Anesthesiologists (ASA)- Performance status of 1 to 3
• •Women of child bearing potential must practice adequate contraception and refrain from breast feeding. Female patients must have a negative pregnancy test within 7 days of treatment
• •Informed consent