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Preemptive Low-dose Epidural Ketamine for Preventing Chronic Post-thoracotomy Pain | Clinical Trials | Clareo Health

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Preemptive Low-dose Epidural Ketamine for Preventing Chronic Post-thoracotomy Pain

NCT01017393•Seoul National University Hospital

Summary

Chronic post-thoracotomy pain is the most common long-term complication that occurs after a thoracotomy with a reported incidence of up to 80%. While thoracic epidural analgesia has become the mainstay for managing acute post-thoracotomy pain, its effect on the chronic post-thoracotomy pain seems questionable. The objective of this prospective, double-blinded, randomized, controlled trial was to assess the effect of preemptive low-dose epidural ketamine in addition to preemptive thoracic epidural analgesia on the incidence of chronic post-thoracotomy pain.

Eligibility

Age

19 - 81 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients undergoing surgery with a thoracotomy incision

Exclusion Criteria

•history of previous thoracic surgery, chronic pain, psychiatric disease, cardiac or vascular disease, neurologic deficits, or contraindications to epidural catheterization such as coagulopathy, or localized or systemic infection

Locations (1)

Seoul National University Hospital

Seoul, Seoul, South Korea

Key Dates

Start Date

April 1, 2004

Primary Completion Date

June 1, 2005

Completion Date

June 1, 2005

Last Updated

November 20, 2009

Enrollment

209

ACTUAL participants

Conditions

Chronic Post-thoracotomy Pain

Interventions

Ketamine

DRUG

ketamine free

DRUG

SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery

NCT07436806

Chronic Post-thoracotomy PainNeuropathic Pain+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 20, 2009Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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