Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
AstraZeneca
Age
18–78
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Type 2 diabetes
18-78 years of age
Taking stable dose of metformin immediate release (IR) or XR ≥850 mg and ≤1500 mg as monotherapy for at least 8 weeks prior to screening
Glycosylated hemoglobin A1C (A1C) 7.5-11.5% at screening
Fasting C-peptide: ≥1.0 ng/mL
FPG≥126 mg/dl obtained at the Day -7 visit
Body mass index (BMI): ≤ 40kg/m²
A1C ≥ 7.0% and ≤ 11.0% obtained at the Day -7 visit for randomization
You may not be if
Women of childbearing potential unable or unwilling to use acceptable birth control
Women who are pregnant or breastfeeding
Significant cardiovascular history
Active liver disease
Renal impairment
Clareo Health | Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg
