Loading clinical trials...

COMPLETEDPHASE1

AZD8566 Food Effect/Microtracer Study

An Open, Randomised, Phase I, 2-Period Crossover Trial to Investigate the Absolute Bioavailability and the Effect of Food on the Oral Bioavailability of AZD8566 in Healthy Volunteers

NCT00866385•AstraZeneca

View on ClinicalTrials.gov

Summary

A study designed to look at how the drug AZD8566 is taken up by the body when given with or without food. In some subjects a comparison will be made with a very small labelled microdose given into a vein.

Eligibility

Age

18 - 55 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Provision of written informed consent
•Clinically normal physical findings and laboratory values as judged by the investigator with normal ECG
•Females who are permanently or surgically sterile or post-menopausal and males

Exclusion Criteria

•History of any convulsions or seizures
•History of infection or risk of infection due to recent surgery or trauma
•History or presence of conditions know to interfere with the absorption, distribution, metabolism and excretion of the study drug

Locations (1)

Research Site

Nottingham, United Kingdom

Key Dates

Start Date

March 1, 2009

Primary Completion Date

March 1, 2009

Completion Date

April 1, 2009

Last Updated

June 9, 2009

Enrollment

ACTUAL participants

Conditions

Healthy Volunteer Study

Interventions

AZD8566

DRUG

AZD8566 IV carbon labelled

DRUG

Muscle Vibration as a Countermeasure Against Hypoactivity-induced

NCT07021079

Vibration TherapyHealthy Volunteer Study+1 more

View study

COMPLETEDPHASE1

A Phase 1 Study of CG001419 Administered Orally in Healthy Subjects

NCT06636500

Healthy Volunteer StudyPain Management

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 9, 2009Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

AZD8566 Food Effect/Microtracer Study

Inclusion Criteria

Exclusion Criteria

Muscle Vibration as a Countermeasure Against Hypoactivity-induced

A Phase 1 Study of CG001419 Administered Orally in Healthy Subjects

Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/Ruzasvir

Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe

Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527

Ibuprofen Suspension Bioequivalence Study