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Sodium Bicarbonate Versus Saline for the Prevention of Contrast-induced Nephropathy in Patients Undergoing Coronary Angiography
Contrast-induced nephrophaty (CIN) accounts for more than 10% of hospital-acquired renal failure. Hydration with sodium bicarbonate is more protective than isotonic saline in animals. Limited data are available in humans. We compared the efficacy of sodium bicarbonate versus isotonic saline to prevent CIN in a large population of patients with renal dysfunction undergoing coronary angiography or intervention.
Age
All ages
Sex
ALL
Healthy Volunteers
No
Ospedale Misericordia e Dolce
Prato, Prato, Italy
Start Date
January 1, 2005
Completion Date
March 1, 2006
Last Updated
May 8, 2012
500
ACTUAL participants
Sodium Bicarbonate
DRUG
Isotonic Saline
DRUG
Lead Sponsor
Ospedale Misericordia e Dolce
NCT06429345
NCT04864847
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06418542