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OBJECTIVE: To compare lispro insulin and regular insulin in the glycemic control of patients with liver cirrhosis and type 2 diabetes subjects. METHODS: 108 patients with liver cirrhosis and type 2 diabetes were randomly treated with regular insulin or lispro. After 122 weeks a cross-over was carried out and patients followed-up for 122 weeks. Then, all patients received a standard breakfast of 145 kcal following 12 U.I. of regular insulin or lispro, and C-peptide and insulin serum levels were determined over 300 minutes.
Age
48 - 67 years
Sex
ALL
Healthy Volunteers
No
Department of Medicine
Naples, Naples, Italy
Last Updated
August 8, 2007
lyspro
DRUG
regular insulin
DRUG
Lead Sponsor
University of Campania Luigi Vanvitelli
NCT05597488
NCT07051005
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View ClinicalTrials.gov Terms and ConditionsNCT00001987