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Mitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Therapy | Clinical Trials | Clareo Health

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Mitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Therapy

Mitral Valve Reconstruction in Patients With Chronic Heart Failure and Secondary Mitral Insufficiency: Identification of Predictors for a Successful Therapy

NCT00348829•University of Leipzig

View on ClinicalTrials.gov

Summary

The aim of the study is to evaluate hemodynamic and echocardiographic parameters in patients with secondary mitral insufficiency and CHF. 1. Identification of hemodynamic parameters as predictor for a successful mitral valve reconstruction in CHF patients. 2. Collection of clinical factors for the assessment of the postoperative course after mitral valve reconstruction in CHF patient.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Age \> 18 years old
•2. Dilatative Cardiomyopathy with LVEF \< 35%
•3. NYHA III oder IV under maximal medical treatment
•4. Angiographic and hemodynamic MI \> II° (LAP- mean pressure \> 15-20 mmHg; LA v-wave-oder PCWP v-wave \> 35 mmHg under exercise)
•5. Echocardiographic MI \> II°
•6. At least 1 hospitalization for heart failure before OP

Exclusion Criteria

•1. Secondary Cardiomyopathy by vitium cordis
•2. Planned secondary procedure like CABG, aortic valve surgery, surgery of the tricuspid valve etc
•3. Inclusion in another trial
•4. Euro-Score \> 30%
•5. Former valve operation or CABG

Locations (1)

Heart Center Leipzig GmbH, University Leipzig

Leipzig, Germany

Key Dates

Start Date

June 1, 2006

Primary Completion Date

December 1, 2008

Completion Date

September 1, 2012

Last Updated

October 27, 2016

Enrollment

ACTUAL participants

Conditions

Chronic Heart FailureMitral Insufficiency

Interventions

mitral valve repair

PROCEDURE

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 27, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Mitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Therapy

Inclusion Criteria

Exclusion Criteria

Impact of YOGA on the Quality of Life and Well-being of Heart Failure Patients

Effectiveness of Low -Versus High -Volume High -Intensity Interval Training in Patients With Chronic Heart Failure

Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

AltaValve Pivotal Trial

Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

Effect of Empagliflozin on Quality of Life in Chronic Heart Failure Patients With Diabetes Mellitus Type II