Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Southern California
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Pathologic diagnosis of Non-Hodgkin's Lymphoma of the mantle cell sub-type lymphoma only, as determined by morphologic assessment and consistent immunophemotypic markers
Newly diagnosed and patients who have received prior treatment are eligible
Measurable or evaluable disease
Karnofsky performance status greater or equal to 50%
Men and women, age greater or equal to 18 years old
AGC greater or equal to 1.0; platelets greater or equal to 75,000; Hemoglobin greater or equal to 8.0 (unless because of lymphomatous infiltration of the marrow)
Creatinine less than 2.0; bilirubin less than 2.0; SGOT less than 3 times upper limit of normal (unless elevations are due to lymphomatous involvement)
Women of child bearing potential must have negative pregnancy test within 14 days of study entry.
Signed informed consent
You may not be if
History of congestive heart failure or significant cardiac disease
Prior exposure to either fludarabine or mitoxantrone. Prior exposure to rituximab allowed
Active infection
HIV seropositive
Pregnant or lactating females
Second active malignancy, other than squamous cell skin cancer,in-situ cervical cancer, or history of other cancer diagnosed within the preceding 5 years
Presence of psychological or emotional disorders which would make valid informed consent impossible
