A Study on Hydroxocobalamin Given to Healthy Individual to Monitor Symptoms

Patients will be recruited at Brigham and Women's Hospital (BWH), at both the main campus and 850 Boylston Street locations. Healthy subjects may be identified as family members of patients who are picking them up from colonoscopy procedures or through the Mass General Brigham Rally system. Flyers and emails will inform interested subjects of the trial and will assist with recruitment. Patients may be identified by their physician or by a research coordinator with physician permission. Patients identified by their healthcare providers who may meet entry criteria would be approached by a study team member to explain about the trial in more detail and to offer participation. In collaboration with their physician, the patient will decide whether to consent and participate. We aim to enroll up to 10 individuals for the study. Individuals will be requested to maintain their diets in their usual intake and avoid those foods which they are aware that may induce diarrhea or looser stools for them. Patients will be given different oral doses of hydroxocobalamin to assess tolerability.