Gut Microbiota and Bacterial Translocation in Restless Legs Syndrome

Exclusion Criteria

• •Patient
• •Presence of digestive, inflammatory, psychiatric or neurological pathologies.
• •C-reactive protein \> 10mg/l (marker of acute inflammation)
• •Presence of moderate-to-severe sleep apnea syndrome (apnea-hypopnea index \>15/h).
• •History of iron supplementation within 6 months.
• •Use of treatments known to aggravate or cause RLS, such as antidepressants, neuroleptics, antihistamines or lithium.
• •Refusal of consent after information
• •legally protected adult (guardianship, curatorship)
• •Pregnant or breast-feeding women
• •Patient not affiliated to or not benefiting from a social security system.
• •Control
• •Presence of gastrointestinal, inflammatory, psychiatric or neurological diseases.
• •C-reactive protein \> 10mg/l (marker of acute inflammation).
• •Presence of PLM in sleep (threshold \>15 per hour of sleep).
• •Treatment with antidepressants, neuroleptics, antihistamines, lithium, antiepileptics, benzodiazepines, hypnotics, opiates, dopaminergic agonists, levodopa, alpha-2delta ligands.
• •Presence of moderate to severe sleep apnea syndrome (apnea-hypopnea index \>15/h)
• •Refusal of consent after information
• •legally protected adult (guardianship, curatorship)
• •Pregnant or breast-feeding woman
• •Participant not affiliated to a social security scheme or not benefiting from such a system.